TOX3 plays a role in regulating calcium-dependent transcription and interacts with cAMP-response-element-binding protein (CREB) and CREB-binding protein (CBP). [7] It also increase

Jan 15, 2026 · TOX3 (TOX High Mobility Group Box Family Member 3) is a Protein Coding gene. Diseases associated with TOX3 include Restless Legs Syndrome and Sporadic Breast Cancer

Our findings establish TOX3 as a driver for excessive gluconeogenesis through activating hepatic FoxO1 transcription. TOX3 could serve as a promising target for preventing and trea

Mar 18, 2026 · Here, we profile nearly 2,000 transcriptional regulators across multiple mouse organs and identify Tox3 as a key coactivator of Atoh1 in the cerebellum. Loss of Tox

Jan 11, 2013 · TOX3 belongs to the large and diverse family of HMG-box proteins that function as architectural factors in the modification of chromatin structure by bending and un

Jan 4, 2025 · TOX3 gene variant could be associated with painful restless legs. TOX high mobility group box family member 3 (TOX3) is one such gene, in which SNPs have been found

Mar 1, 2024 · Furthermore, Tox3 knockout can both potently protect against as well as ameliorate hyperglycemia and gluconeogenesis in diabetic mice induced by high-fat diet. There

TOX3 plays a role in regulating calcium-dependent transcription and interacts with cAMP-response-element-binding protein (CREB) and CREB-binding protein (CBP). [7] It also increase

These results indicated that TOX3 is a prognostic indicator and promising immunomodulatory factor in lung adenocarcinoma. Future studies investigating the role of TOX3 in lung canc

In this study, we characterize the protein expression of TOX3 in breast tumors with respect to various clinical and pathological characteristics and explore the correlation between